Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 5 (Feb. 27, 2001), pp. 2550-2554 (5 pages) The yeast transcriptional repressor Tup1, tethered to DNA, ...
To initiate transcription, the holoenzyme (RNA polymerase [RNAP] in complex with σ factor) loads the promoter DNA via the flexible loading gate created by the clamp and β-lobe, yet their roles in DNA ...
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